Presley’s Bariatric Complication; Acromegaly Win; Tele-Monitor Diabetic Foot Ulcers

An autopsy report showed that Lisa Marie Presley, the only child of Elvis Presley, died of a small-bowel obstruction “caused by adhesions that developed after bariatric surgery years ago.” (NBC News)

Treatment with the investigational octreotide subcutaneous depot CAM2029 increased IGF-1 response rate and reduced symptom burden in patients with acromegaly in the phase III ACROINNOVA 2 trial, developer Camurus announced.

Adding daily metformin (1,700 mg) to lifestyle intervention reduced the risk of developing diabetes by 17% compared with lifestyle intervention alone, a randomized trial of Chinese adults with elevated glucose levels found. (The Lancet Diabetes & Endocrinology)

TheracosBio announced the commercial availability of bexagliflozin (Brenzavvy), a recently FDA-approved SGLT2 inhibitor, through Mark Cuban Cost Plus Drugs Company.

A telemedical monitoring intervention for diabetic foot ulcers that relied on expert nurses roughly halved the number of total days spent in hospital over 12 months compared with conventional follow-up (mean 7.1 vs 13.4 days, respectively) while lowering cumulative costs. (The Lancet Regional Health — Europe)

The U.S. Preventive Services Task Force released its final research plan on screening for chronic kidney disease last week.

Eli Lilly announced plans to buy obesity drug developer Versanis for $1.93 billion during early-stage trials of its investigational drug bimagrumab — a first-in-class monoclonal antibody that binds activin type II A and B receptors, which reduces fat mass and increases lean muscle mass in patients with obesity and type 2 diabetes.

Only 20% of American adults checked off at least four factors of a healthy lifestyle — never smoking, moderate or lighter alcohol consumption, healthy diet, sufficient physical activity, and a healthy BMI — in March 2020. (JAMA Network Open)

Studies on the health affects of the “forever chemicals” PFAS often received little media attention, especially if the research wasn’t accompanied by a press release. “It’s a shame that only a small slice of this science is reaching the public,” said lead author Rebecca Fuoco, MPH, of the Green Science Policy Institute in Berkeley, California, in a statement. (Environmental Health)

Novo Nordisk sued three Florida compounding pharmacies for illegally selling products they claim contain semaglutide, the active ingredient in the company’s type 2 diabetes and weight loss drugs (Ozempic, Wegovy). (Reuters)