Entresto for Pre-Heart Failure; Afib and Dementia; DIY 12-Lead ECG for Patients

Days of greater local ambient ozone pollution coincided with excess hospital admissions for cardiovascular disease in China. (European Heart Journal)

FDA and CDC officials sent a letter to Florida surgeon general Joseph Ladapo, MD, PhD, stressing that his claim of excess strokes and heart attacks in people vaccinated against COVID-19 is incorrect, misleading, and potentially harmful. (ABC News)

Are women not affected by the health risks associated with physically demanding jobs? (European Journal of Preventive Cardiology)

In adolescent athletes in the U.K., sudden cardiac death is more likely to be traced back to arrhythmogenic cardiomyopathy, coronary artery anomalies, and commotio cordis than in sedentary peers. (Journal of the American College of Cardiology)

Patients with pre-heart failure with preserved ejection fraction had some improvements in NT-proBNP and echocardiographic parameters taking sacubitril/valsartan (Entresto) in the small PARABLE trial. (JAMA Cardiology)

Is in-hospital observation on oral diuretics actually helpful after treatment for acute decompensated heart failure? (Circulation: Heart Failure)

Depressive symptoms may be a risk factor for ischemic and hemorrhagic strokes alike, according to the international INTERSTROKE study. What’s more, pre-admission depression was associated with poor post-stroke recovery. (Neurology)

Korean registry data suggest that routine genotyping helps identify East Asians with a CYP2C19 loss-of-function allele who are at greater risk of clotting events on clopidogrel after percutaneous coronary intervention. (JACC: Cardiovascular Intervention)

Large disparities exist in access to mechanical thrombectomy for stroke between high- and low-income countries. (Circulation)

There may be a difference in performance between first-line stent retrievers and aspiration devices for the endovascular treatment of a larger thrombus. (Stroke)

In clinical practice, a person’s systolic blood pressure varied by 10.6 mmHg on average visit-to-visit, and very little of this variance could be explained by patient characteristics. (Circulation: Cardiovascular Quality and Outcomes)

A genetic test helped guide treatment for hypertension, bringing blood pressure control to 94.0% in 4 days on average in a pilot study. (Science Translational Medicine)

Left atrial appendage occlusion appeared safe and effective for cancer patients with atrial fibrillation (Afib) in a small single-institution study. (JACC: CardioOncology)

People with an Afib diagnosis had a modestly higher risk of subsequent dementia based on hospital records. (Journal of the American Heart Association)

With some education, laypeople were able to obtain their own patch-type, wireless 12-lead ECGs without physical contact with medical staff. (Scientific Reports)