Uncovering a cellular process that leads to inflammation
Cedars-Sinai investigators have identified several steps in a cellular process responsible for triggering one of the body's important inflammatory responses. Their findings, published in the…
Browsing Tag
Immune System; Crohn
In search of inflammatory Achilles heel: Neutrophils instruct macrophages to form…
When our bodies become infected, various immune responses are triggered, starting with a release of granulocytes, white blood cells containing special enzymes that make up about half or more…
Environmental chemicals increase risk of inflammatory bowel disease: Using multiple…
Using multiple research platforms, including a machine learning approach, investigators have identified environmental factors that promote gastrointestinal inflammation.
Inflammatory bowel…
Innate immunity: The final touch for antimicrobial defense
If bacteria enter the body, it often takes just a few minutes for the innate immune system to recognise them as foreign and set the immune defence in motion. Receptors of the immune system…
New potential treatment for graft-versus-host-disease and other inflammatory…
A new study led by UC Davis Health researchers showed that blocking IL-6 and TNF cytokines provides a more effective approach to preventing life-threatening graft-versus-host-disease (GVHD),…
When macrophages let off steam: Changes in cell metabolism protect macrophages from…
New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages. Danger…
Rare disorder offers roadmap for understanding roots of inflammatory disease
Yale researchers have discovered the underlying genetic cause of a rare childhood disorder that mimics inflammatory bowel disease, a finding that may help researchers uncover the roots of a…