Rainbow Fentanyl Warning; In Utero Hurricane Trauma; Aripiprazole LAI Heads to FDA

Following a recent Drug Enforcement Administration warning, schools are notifying students about “rainbow” fentanyl that looks like brightly colored candy. (CNN)

Cognitive belief updating tended to be optimistic as soon as 4 hours after a first ketamine infusion in people with treatment-resistant depression in an observational case-control study. (JAMA Psychiatry)

Pregnant women who endured 2012’s Superstorm Sandy were more likely to have children with depression, anxiety, and attention-deficit/disruptive behavioral disorders than those who didn’t live through a major weather-related disaster. (Journal of Child Psychology and Psychiatry)

Hospital EmPATH (emergency psychiatric assessment, treatment, and healing) units are moving some patients with mental health crises out of emergency rooms. (Bloomberg)

The FDA accepted Otsuka and Lundbeck’s new drug applications for 2-month, ready-to-use aripiprazole long-acting injectable, seeking an indication for the treatment of schizophrenia in adults and for maintenance monotherapy treatment of bipolar I disorder in adults. The PDUFA date is set for April 27, 2023.

The investigational anti-amyloid beta protofibril antibody lecanemab showed a small but significant reduction in cognitive decline in participants with early Alzheimer’s disease in a phase III trial, drug developers Eisai and Biogen announced.

Hopes remain high 2 years after Oregon residents voted to decriminalize hard drugs and dedicate hundreds of millions of dollars to treatment. (AP)

In a mouse study, 50 mg/day or more of spironolactone reduced heavy alcohol consumption, possibly serving “as a novel pharmacotherapy for alcohol use disorder,” researchers reported in Molecular Psychiatry.

Following a patient death at a New York state psychiatric hospital in Brooklyn caused from neck trauma, police are now investigating the case as a homicide. (New York Times)

Nurses implied that Meghan Trainor’s antidepressants contributed to why her son was in a neonatal intensive care unit, the singer said. (People)