Predicting Crohn’s Relapse; Sex After Hernia Repair; Bacteria and Anti-TNF Response

Distinct blood protein profiles may help predict clinical relapse in Crohn’s disease patients who stop tumor necrosis factor (TNF) inhibitors, and could help pave the way for non-invasive biomarkers to guide anti-TNF withdrawal. (Gut)

What’s better for inguinal hernia repair when it comes to pain during sex: extra-peritoneal or Lichtenstein repair? (Surgery)

Artificial intelligence during colonoscopy would increase intensive surveillance colonoscopies by 35% in the U.S., according to pooled data from randomized trials, a potential boon to cancer detection but also patient burden and healthcare costs. (Clinical Gastroenterology and Hepatology)

What’s the link between rurality, race, and undergoing surgery for colon cancer? (JAMA Network Open)

Can higher dosing of the TNF inhibitor infliximab (Remicade) be enough to optimize early clinical outcomes for children hospitalized with acute severe ulcerative colitis? (Clinical Gastroenterology and Hepatology)

For kids with inflammatory bowel disease (IBD), quicker responses to infliximab were seen in those with an abundance of Bifidobacteriales in the gut, a small study found. (Inflammatory Bowel Diseases)

Even though IBD patients mounted less of a humoral response to COVID-19 vaccines versus healthy controls, this didn’t appear to be due to immune-modifying treatments. (Digestive and Liver Disease)

Two of every five children with Alagille syndrome — an inherited condition marked by cholestasis — no longer had their own livers by adulthood, a large international cohort study found, but those with lower bilirubin levels in childhood were twice as likely to keep their native livers. (Hepatology)

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