Polymyositis Pipeline to Progress with New and Emerging Drugs for Treatment, Analyzes DelveInsight

Las Vegas, USAPolymyositis Pipeline to Progress with New and Emerging Drugs for Treatment, Analyzes , Dec. 08, 2021 (GLOBE NEWSWIRE) — DelveInsight’s ‘Polymyositis Pipeline Insight 2021’ report offers exhaustive global coverage of available, marketed, and pipeline therapies in different phases of clinical development, major pharmaceutical companies working to advance the pipeline space, and future growth potential of the Polymyositis pipeline domain. 

Some of the essential takeaways from the Polymyositis Pipeline report:

• DelveInsight’s Polymyositis Pipeline analysis depicts a robust space with 7+ active players working to develop 7+ pipeline treatment therapies. 
• Some of the key pharmaceutical companies working to develop potential drug candidates to improve the Polymyositis treatment scenario include Cytodyn,  ImmunoForge, Viela Bio, Paean Biotechnology, Kezar Life Sciences Inc, Bristol-Myers Squibb,  Janssen Pharmaceutical, Restem LLC and many others.
• Essential Polymyositis pipeline therapies such as Research programme polymyositis, PF1801, VIB7734, PN-101, KZR-616, Abatacept, Ustekinumab, Umbilical Cord Lining Stem Cells and others are under development in different phases of clinical trials.
• KZR-616 is a novel, first-in-class, selective immunoproteasome inhibitor with broad therapeutic potential across multiple autoimmune diseases developed by Kezar Life Sciences Inc. KZR-616 offers a novel approach to harmonizing the immune system via selective immunoproteasome inhibition.
• Bristol-Myers Squibb is currently recruiting adults with active dermatomyositis or polymyositis for a clinical trial. The goal is to evaluate the effectiveness and safety of a study drug, called abatacept, in combination with standard medicines in improving symptoms of active myositis.
• In September 2021, the US FDA granted Orphan Drug designation to PF1801 for the treatment of polymyositis.
• In October 2020, the US FDA granted Orphan Drug Designations (ODD) for KZR-616 for the treatment of polymyositis (PM) and dermatomyositis (DM). 
• Cytodyn is conducting preclinical studies in several autoimmune diseases including polymyositis, IBS (inflammatory bowel disease), MS (Multiple Sclerosis). 
• VIB7734 is a humanized mAb intended to be a novel treatment for autoimmune diseases where the pathology is driven principally by overproduction of type I interferons and other cytokines secreted by pDCs. VIB7734 was studied in a Phase I clinical trial and the trial demonstrated that VIB7734 was generally well-tolerated and reduced pDC levels.

Request a sample and discover more about the report offerings @ Polymyositis Emerging Therapies

The Polymyositis pipeline report lays down detailed profiles of the pipeline assets, comparative analysis of clinical and non-clinical stage Polymyositis products, inactive and dormant assets, comprehensive assessment of driving and restraining factors, as well as the opportunities and risks in the Polymyositis pipeline landscape.

Polymyositis Overview

Polymyositis is a type of inflammatory myopathy, which refers to a group of muscle diseases characterized by chronic muscle inflammation and weakness. Polymyositis (PM), an autoimmune disorder, develops due to abnormal activation of cytotoxic T lymphocytes (CD8 cells) and macrophages against muscular antigens as well as the strong extrafusal muscular expression of major histocompatibility complex 1 causing damage to the endomysium of skeletal muscles. Polymyositis develops gradually over time, and it rarely affects persons younger than age 18.

Find out more about the disease and recent developments @ Polymyositis Pipeline Assessment 

Polymyositis Pipeline Drugs

Learn more about the novel and emerging Polymyositis pipeline therapies @ Polymyositis Pipeline Analysis

Polymyositis Therapeutics Assessment

The Polymyositis Pipeline report proffers an integral view of the Polymyositis emerging novel therapies segmented by Stage, Product Type, Molecule Type, Mechanism of Action and Route of Administration.

By Product Type

• Mono
• Combination
• Mono/Combination

By Stage

• Discovery 
• Pre-clinical
• Phase I
• Phase II
• Phase III
• Pre-registration
• Inactive candidates

By Route of Administration

• Oral
• Intravenous
• Subcutaneous

By Molecule Type 

• Gene therapy
• Stem cell therapy
• Small molecules
• Recombinant protein

By Mechanism of Action

• T cell activation inhibitors
• Cell replacements
• Mitochondria replacements
• Glucagon like peptide 1 receptor agonists
• Dendritic cell inhibitors

Scope of the Polymyositis Pipeline Report 

• Coverage: Global 
• Major Players: Cytodyn,  ImmunoForge, Viela Bio, Paean Biotechnology, Kezar Life Sciences Inc, Bristol-Myers Squibb,  Janssen Pharmaceutical, Restem LLC and many others.
• Key Polymyositis Pipeline Therapies: Research programme polymyositis, PF1801, VIB7734, PN-101, KZR-616, Abatacept, Ustekinumab, Umbilical Cord Lining Stem Cells,  and many others.

Dive deep into rich insights for emerging therapies and assessment, visit @ Polymyositis Emerging Therapies 

Table of Contents 

For further information on the Polymyositis current pipeline therapeutics, reach out @ Polymyositis Ongoing Clinical Trials 

Track and assess a candidate’s clinical development journey through Actionable Intelligence and Comparative Therapeutic Assessment 

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