Obesity Changes Brain Forever? More Metformin/Long COVID Data; Ro Stops Wegovy Ads

Obesity-related brain changes may not be reversible, a small study suggested. (Nature Metabolism)

Nearly a quarter of adults with thyroid nodules also have diabetes, according to a study of nearly 400 patients. (Journal of Clinical Medicine Research)

Metformin may help to prevent long COVID. (The Lancet Infectious Diseases)

Patients with type 2 diabetes and cardiovascular disease who have higher out-of-pocket costs were less likely to start on a GLP-1 receptor agonist or SGLT2 inhibitor. (JAMA Network Open)

A new viewpoint published in JAMA Pediatrics focuses on a single recommendation in the controversial American Academy of Pediatrics obesity guideline, which specifies that medication should be offered in addition to lifestyle interventions.

Mothers with higher exposure to the family of forever chemicals PFAS during pregnancy were more likely to have kids with obesity. (Environmental Health Perspectives)

Telehealth company Ro paused its advertising of semaglutide (Wegovy) amid shortages. (STAT)

Why are these weight-loss drugs so much more popular in the U.S. than Europe? (Forbes)

Exercise can counteract the genetic risk for diabetes, according to a new study. (British Journal of Sports Medicine)