Moderna says its low-dose COVID shots work for kids under 6

The younger the child, the smaller the dose being tested. Moderna said a quarter of the dose it uses for adults worked well for youngsters under age 6.

Moderna enrolled about 6,900 tots in a study of the 25-microgram doses. Early data showed after two shots, youngsters developed virus-fighting antibody levels just as strong as young adults getting regular-strength shots, the company said in a press release.

Moderna said the small doses were safe, and the main side effects were mild fevers like those associated with other commonly used pediatric vaccines.

Once Moderna submits the data to the FDA, regulators will debate whether to authorize emergency use of the small doses for tots. If so, the Centers for Disease Control and Prevention then will decide whether to recommend them.

While COVID-19 generally isn’t as dangerous to youngsters as to adults, some do become severely ill. The CDC says about 400 children younger than 5 have died from COVID-19 since the pandemic’s start. The omicron variant hit children especially hard, with those under 5 hospitalized at higher rates than at the peak of the previous delta surge, the CDC found.

COVID-19 vaccines in general don’t prevent infection with the omicron mutant as well as they fended off earlier variants — but they do still offer strong protection against severe illness.