LSD Win in Depression; Rethinking Placebo Effect; 1 in 4 Teens Misuse Stimulants

High doses of lysergide, better known as LSD, significantly improved symptoms of major depression within 6 weeks, meeting the primary endpoint in a phase II trial, developer MindMed announced.

A daily helping of raw walnuts for 6 months helped improve attention span in adolescents. (EClinicalMedicine)

In a nationwide survey conducted by Myriad Genetics, 77% of people said they’ve used at least one unhealthy coping mechanism or addictive behavior to manage their mental health.

Should we rethink how we view the placebo effect? (The Lancet Psychiatry)

In a study looking at prenatal exposure to antiseizure medications and psychiatric disorders in offspring, valproate was tied to an increased risk of various psychiatric disorders, while topiramate (Topamax) was linked with a higher risk for attention deficit-hyperactivity disorder (ADHD) specifically and levetiracetam (Keppra) to a higher risk of anxiety and ADHD. (JAMA Neurology)

Reproductive system disorders among women were associated with two- to threefold increased odds of having a psychiatric disorder, according to a meta-analysis of 31 studies. (JAMA Network Open)

Social media giants Meta, TikTok, Snap, and Google asked a federal judge to dismiss a slew of teen-addiction lawsuits. (Bloomberg Law)

Suicides increased in 2021, reaching their highest level since 2018, new CDC data showed. And from 2016 to 2020, the emergency department visit rate for suicidal ideation was highest for people ages 14 to 18, according to another CDC report.

During pregnancy, mothers who underwent eight sessions of brief interpersonal psychotherapy had significantly lower rates of prenatal depression compared with those who only had usual care enhanced with maternity support services. (JAMA Psychiatry)

Up to one in four adolescents in the U.S. reported misusing prescription stimulants used to treat ADHD. (JAMA Network Open)

A man with untreated schizophrenia died after spending 3 weeks in solitary confinement in an Indiana jail, according to a lawsuit. (CNN)

Could psychedelic drugs help to treat long COVID? (Time)