says Professor Daniela Carnevale, Department of Angiocardioneurology and Translational Medicine of Neuromed and full professor at the Sapienza University of Rome and senior author of the publication.
“ABC” as Therapeutic Potential
The study helped the team reconstruct the entire path of nerve fibers, up to the central nervous system “At this point , we were able to see that signals coming from the plaque, once they reach the brain, influence the autonomic nervous system through the vagus nerve (the one portion of the nervous system controlling most of our organs and visceral functions, ed) down to the spleen. Here, specific immune cells are activated and enter the blood circulation, leading to the progression of the plaques themselves ,” says Carnevale.
The authors defined this real circuit as “ABC” or “artery-brain circuit”. These lines of evidence state that the stability of atherosclerotic plaque is one of the most clinically relevant traits in evaluating the severity of the disease.
The findings also set a new target for innovative therapies for atherosclerosis through its significant translational potential.
Source: Medindia
For all the latest Health News Click Here
For the latest news and updates, follow us on Google News.
Denial of responsibility! NewsBit.us is an automatic aggregator around the global media. All the content are available free on Internet. We have just arranged it in one platform for educational purpose only. In each content, the hyperlink to the primary source is specified. All trademarks belong to their rightful owners, all materials to their authors. If you are the owner of the content and do not want us to publish your materials on our website, please contact us by email – [email protected]. The content will be deleted within 24 hours.
