Hepatic Cirrhosis Market Evolving at a Rapid Pace, Predicts DelveInsight | Key Companies Active in the Domain – Madrigal, Zydus, Can-Fite BioPharma, Bristol-Myers Squibb, Boehringer Ingelheim, Grifols, Akero

New York, USA, April 27, 2023 (GLOBE NEWSWIRE) — Hepatic Cirrhosis Market Evolving at a Rapid Pace, Predicts DelveInsight | Key Companies Active in the Domain – Madrigal, Zydus, Can-Fite BioPharma, Bristol-Myers Squibb, Boehringer Ingelheim, Grifols, Akero

According to DelveInsight’s’ estimates, the hepatic cirrhosis market in 7MM is expected to show positive growth during the forecast period (2023–2032), mainly attributed to new product launches, a robust pipeline of emerging therapies, and government support for clinical development. 

DelveInsight’s Hepatic Cirrhosis Market Insights report includes a comprehensive understanding of current treatment practices, hepatic cirrhosis emerging drugs, market share of individual therapies, and current and forecasted market size from 2019 to 2032, segmented into 7MM [the United States, the EU-4 (Italy, Spain, France, and Germany), the United Kingdom, and Japan].

Key Takeaways from the Hepatic Cirrhosis Market Report

• As per DelveInsight analysis, the hepatic cirrhosis market is expected to grow positively owing to several underline factors during the study period (2019–2032).
• Through DelveInsight’s analysis, it can be observed that hepatic cirrhosis cases show an increasing trend in the forecasted period in the United States. 
• Leading hepatic cirrhosis companies such as Madrigal Pharmaceuticals, Inc., Zydus Therapeutics Inc., PharmaIN, Rebiotix Inc., Grifols Therapeutics LLC, Exelixis, Vir Biotechnology, Inc., Lipocine Inc, Vedanta Biosciences, Inc., NGM Biopharmaceuticals, Inc, BioVie Inc., Ocelot Bio, Inc, Genfit, CymaBay Therapeutics, Inc., Can-Fite BioPharma, Bristol-Myers Squibb, Boehringer Ingelheim, Akero Therapeutics, Inc, HighTide Biopharma Pty Ltd, Intercept Pharmaceuticals, Kowa Research Institute, Inc., COUR Pharmaceutical Development Company, Inc., and others are developing novel hepatic cirrhosis drugs that can be available in the hepatic cirrhosis market in the coming years.
• Some of the key therapies for hepatic cirrhosis treatment include Resmetirom, Saroglitazar Magnesium, PHIN-214 Subcutaneous injection, RBX7455, Albutein 20% Injectable Solution, Cabozantinib, VIR-2218, VIR-3434, LPCN 1148, VE303, Aldafermin, BIV201 continuous infusion, OCE-205, Elafibranor, Seladelpar, Namodenoson, BMS-986263, BI 685509, EFX, HTD1801, Bezafibrate, K-877-ER, CNP-104, MGL-3196, and others.
• Several hepatic cirrhosis therapies are awaiting approval, while some therapies are in the advanced stages of development. 

Discover which therapies are expected to grab the major hepatic cirrhosis market share @ Hepatic Cirrhosis Market Report

Hepatic Cirrhosis Overview

Hepatic Cirrhosis is a late-stage liver condition in which good liver tissue is replaced with scar tissue, causing permanent damage to the liver. Many liver disorders and conditions cause cell death and inflammation in healthy liver cells. This is followed by cell repair and, as a result of the repair process, tissue scarring. Scar tissue obstructs blood flow through the liver, slowing its capacity to metabolize nutrients, hormones, medicines, and natural poisons. It also lowers the liver’s production of proteins and other chemicals. Cirrhosis eventually prevents the liver from functioning normally. Cirrhosis in its advanced stages is lethal.

Cirrhosis is most commonly caused by hepatitis C virus (HCV), alcoholic liver disease, and nonalcoholic steatohepatitis (NASH) in the industrialized world, whereas hepatitis B virus (HBV) and HCV are the most common causes in the poor world. Cirrhosis can also be caused by other conditions such as autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, hemochromatosis, Wilson disease, alpha-1 antitrypsin deficiency, Budd-Chiari syndrome, drug-induced liver cirrhosis, and chronic right-sided heart failure. As the liver’s function progressively declines, liver cirrhosis frequently goes untreated and unreported. As a result, it is critical to have regular exams. Abdominal ultrasonography, elastography, body magnetic resonance imaging (MRI), magnetic resonance cholangiopancreatography (MRCP), biopsies, and other imaging tests are used for hepatic cirrhosis diagnosis.

Hepatic Cirrhosis Epidemiology Segmentation

The hepatic cirrhosis epidemiology section provides insights into the historical and current hepatic cirrhosis patient pool and forecasted trends for the seven individual major countries. It helps recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders.

The hepatic cirrhosis market report proffers epidemiological analysis for the study period 2019–2032 in the 7MM segmented into:

• Total Hepatic Cirrhosis Prevalent Cases
• Hepatic Cirrhosis Gender-specific Cases
• Hepatic Cirrhosis Age-specific Cases 
• Hepatic Cirrhosis Etiology-specific Cases

Download the report to understand which factors are driving hepatic cirrhosis epidemiology trends @ Hepatic Cirrhosis Epidemiological Insights

Hepatic Cirrhosis Treatment Market 

Cirrhosis treatment techniques may differ depending on the disease stage and underlying etiology. In general, the treatment goals for compensated cirrhosis are to slow, stop, or reverse fibrosis progression and prevent decompensation events. In contrast, treatment goals for decompensated cirrhosis are to prevent further decompensation and death (e.g., by improving liver function) and to treat complications related to portal hypertension. EPCLUSA (Gilead Sciences) has been licensed by the US Food and Drug Administration to treat adult patients with chronic hepatitis C virus (HCV), both with and without cirrhosis. EPCLUSA is licensed for use in patients with moderate to severe cirrhosis in combination with the medication ribavirin.

Hepatic cirrhosis patients are also given statins and vaptans. Tolvaptan is recommended for hepatic cirrhosis treatment when renal function is preserved. Statins used in cirrhosis include atorvastatin, fluvastatin, lovastatin, pitavastatin, and simvastatin. Because of their pleiotropic qualities, statins are beneficial in the treatment of dyslipidemia in patients with liver disease. These qualities, such as alleviating endothelial dysfunction or possessing antioxidant, antifibrotic, anti-inflammatory, antiproliferative, antiangiogenic, proapoptotic, or immunomodulatory properties, are independent of their influence on cholesterol levels.

To know more about hepatic cirrhosis treatment, visit @ Hepatic Cirrhosis Treatment Drugs 

Key Hepatic Cirrhosis Therapies and Companies

• Resmetirom: Madrigal Pharmaceuticals, Inc.
• Saroglitazar Magnesium: Zydus Therapeutics Inc.
• PHIN-214 Subcutaneous injection: PharmaIN
• RBX7455: Rebiotix Inc.
• Albutein 20% Injectable Solution: Grifols Therapeutics LLC
• Cabozantinib: Exelixis
• VIR-2218: Vir Biotechnology, Inc
• VIR-3434: Vir Biotechnology, Inc.
•  LPCN 1148: Lipocine Inc
• VE303: Vedanta Biosciences, Inc.
• Aldafermin: NGM Biopharmaceuticals, Inc
• BIV201 continuous infusion: BioVie Inc.
• OCE-205: Ocelot Bio, Inc
• Elafibranor: Genfit
• Seladelpar: CymaBay Therapeutics, Inc.
• Namodenoson: Can-Fite BioPharma
• BMS-986263: Bristol-Myers Squibb
• BI 685509: Boehringer Ingelheim
• EFX: Akero Therapeutics, Inc
• HTD1801: HighTide Biopharma Pty Ltd
• Bezafibrate: Intercept Pharmaceuticals
• K-877-ER: Kowa Research Institute, Inc.
• CNP-104: COUR Pharmaceutical Development Company, Inc.
• MGL-3196: Madrigal Pharmaceuticals, Inc.

Learn more about the FDA-approved drugs for hepatic cirrhosis @ Drugs for Hepatic Cirrhosis Treatment 

Hepatic Cirrhosis Market Dynamics

The hepatic cirrhosis market is expected to change in the coming years due to increased disease awareness and healthcare spending around the world, which will increase the size of the hepatic cirrhosis market and allow drug manufacturers to extend their hepatic cirrhosis market penetration. The United States is predicted to account for the greatest part of the hepatic cirrhosis market in the 7MM due to favorable reimbursement scenarios, increased R&D spending in pharmaceutical companies and research institutes for new medication development, and the presence of key players in the domain. In addition, due to increased awareness about new treatment options and a mature regulatory framework, Europe is expected to be the second-largest market for liver cirrhosis therapy throughout the forecast period. 

Moreover, the Japanese market for liver cirrhosis treatment is expected to expand rapidly during the forecast period (2023–2032). The region’s hepatic cirrhosis market growth can be ascribed to an increase in the prevalence of liver illnesses and an improvement in healthcare infrastructure. Furthermore, the hepatic cirrhosis pipeline is highly robust; many possible therapies are being studied for hepatic cirrhosis treatment, and it is safe to assume that the therapeutic space will substantially impact the hepatic cirrhosis market throughout the forecast period.

However, certain factors may affect the growth of the hepatic cirrhosis market. The hepatic cirrhosis market growth may be offset by failures and discontinuation of emerging therapies, unaffordable pricing, market access and reimbursement issues, and a shortage of healthcare specialists. In addition, the undiagnosed, unreported cases and the unawareness about the disease may also impact the hepatic cirrhosis market growth.

Scope of the Hepatic Cirrhosis Market Report

• Therapeutic Assessment: Hepatic Cirrhosis current marketed and emerging therapies
• Hepatic Cirrhosis Market Dynamics: Attribute Analysis of Emerging Hepatic Cirrhosis Drugs
• Competitive Intelligence Analysis: SWOT analysis and Market entry strategies
• Unmet Needs, KOL’s views, Analyst’s views, Hepatic Cirrhosis Market Access and Reimbursement

Discover more about hepatic cirrhosis drugs in development @ Hepatic Cirrhosis Clinical Trials

Table of Contents

Related Reports

Hepatic Cirrhosis Pipeline

Hepatic Cirrhosis Pipeline Insight – 2023 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key hepatic cirrhosis companies, including Clarity Pharmaceuticals Ltd, Eli Lilly and Company, Laboratorio Elea Phoenix S.A., PersonGen BioTherapeutics (Suzhou) Co., Ltd., among others.

Hepatic Cirrhosis Epidemiology Forecast

Hepatic Cirrhosis Epidemiology Forecast – 2032 report delivers an in-depth understanding of the disease, historical and forecasted hepatic cirrhosis epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.

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Non-Alcoholic Fatty Liver Disease Market Insights, Epidemiology, and Market Forecast – 2032 report deliver an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key non-alcoholic fatty liver disease companies including AstraZeneca, Novartis, Pfizer, Roche, among others.

Non-Alcoholic Fatty Liver Disease Pipeline

Non-Alcoholic Fatty Liver Disease Pipeline Insight – 2023 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key advanced non-alcoholic fatty liver disease companies, including AstraZeneca, Novartis, Pfizer, Roche, among others.

Nonalcoholic Steatohepatitis Epidemiology

Nonalcoholic Steatohepatitis Epidemiology Forecast – 2032 report delivers an in-depth understanding of the disease, historical, and forecasted nonalcoholic steatohepatitis epidemiology in the 7MM.

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