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Fecal Transplant in UC; Cancer Surveillance Lacking in Cirrhosis; Undiagnosed Celiac

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Researchers believe they’ve identified two more reasons why fecal microbiota transplants from certain donors more often induce ulcerative colitis (UC) remissions. (Gut)

AbbVie announced that it is seeking FDA approval for a new indication for upadacitinib (Rinvoq) to treat moderately to severely active Crohn’s disease.

The vast majority of high-risk cirrhosis patients diagnosed with hepatocellular carcinoma didn’t get adequate surveillance ahead of their cancer diagnosis. Researchers have homed in on some reasons why. (JAMA Network Open)

Heard about “No Poop July?” Well, it’s not really a thing, but doctors are warning against it anyhow. (NBC News)

A large meta-analysis of genome wide association studies involving nearly 17,000 cases of Barrett’s esophagus and esophageal cancer identified multiple novel genetic risk loci for the diseases. (Gut)

How to optimize proton pump inhibitor use for treating gastroesophageal reflux in systemic sclerosis. (The Lancet Rheumatology)

In a screening study from Norway, three-fourths of adult celiac disease cases were found to be undiagnosed, and these individuals similarly benefited from a gluten-free diet. (Scientific Reports)

In hepatitis B patients with cirrhosis and alcoholism, the ALDH2 rs671 polymorphism (GA/AA) was found to substantially add to the heightened risk of liver cancer and mortality. (JAMA Network Open)

A prisoner in Missouri who was reportedly aware of his hepatitis C infection faces a criminal charge for exposing a staff member; the inmate allegedly smeared blood and fecal matter on the staffer’s arm during an attempted attack. (Fox2Now)

How do certain foods affect inflammatory bowel disease (IBD) development? (Food Science & Nutrition)

Real-world data from the SPARC IBD registry detail the high disease burden and need for surgery in patients with complicated Crohn’s disease. (Inflammatory Bowel Diseases)

  • Zaina Hamza is a staff writer for MedPage Today, covering Gastroenterology and Infectious disease. She is based in Chicago.

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