Distressing Childhood Dreams; Bilingualism and Epilepsy; Clock-Drawing Test Meets AI

Regular distressing dreams during childhood were significantly associated with higher risks of developing cognitive impairment or Parkinson’s disease by age 50. (eClinicalMedicine)

Alzheimer’s blood biomarkers of phosphorylated tau and amyloid beta were altered after out-of-hospital cardiac arrest. (JAMA Neurology)

Higher structural network organization in bilingual individuals who had left temporal lobe epilepsy suggested a neuromodulatory effect of bilingualism on whole-brain connectivity in epilepsy. (Neurology)

Exome or genome sequencing in cerebral palsy had a diagnostic yield of 31.1%, similar to other neurodevelopmental disorders, a meta-analysis showed. (JAMA Pediatrics)

The FDA accepted Eisai and Biogen’s application for traditional approval of lecanemab (Leqembi) and plans to hold an advisory committee meeting before its July 6 decision.

The agency also cleared Abbott’s blood test to evaluate concussion.

Telomere shortening was linked with early subjective depressive symptoms and cognitive complaints in older adults. (Aging)

Brain inflammation was detectable at the earliest stages of Parkinson’s disease. (Movement Disorders)

College degree attainment was linked with lower dementia incidence in Asian American individuals. (JAMA Network Open)

A digital, AI-enhanced version of the clock-drawing test is being evaluated. (Health IT Analytics)

Here’s a look at potential implications for general neurologists of blood-based biomarkers for neurodegenerative diseases. (Neurology)