Antibody Drug Conjugate Market, a $13.15 billion Industry by 2030 with a CAGR of 14.12 %

New York, United States, June 21, 2022 (GLOBE NEWSWIRE) — The surge in the antibody-drug conjugates market growth is due to rising cancer cases globally, technological advancements in medical technology and the rising geriatric population.

 Insights of the Antibody Drug Conjugates Market:

• North America leads the regional market with a share of almost 29.36% in 2020, having a steady growth rate.
• By Type, the Monoclonal Antibody-drug conjugates led the market in the year 2020.
• By Application, the breast-cancer market dominated the market for ADC. 
• By End-Users, the segment in 2020 was dominated by Hospitals and clinics.

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Key factors boosting the worldwide market growth: –

Antibody-drug conjugates are primarily used in cancer treatment, wherein they are developed to target the cancer cells alone, bypassing the healthy cells. According to Eurostat, cancer was responsible for the deaths of approximately 1.2 million people in Europe, which was 26% of the total deaths in the region. According to the CDC, breast cancer is the second most common type of cancer in women in the US and is responsible for nearly 42,000 deaths each year. Thus, with rising cancer cases globally, the need for antibody-drug conjugates (or ADCs) will boost the overall market growth.

As per UN statistics, globally, the number of people above the age of 65 will rise from 9.3% of the total population in 2020 to 16.0% of the population by 2050. This can be attributed to increased awareness of healthy habits and lifestyles adopted by the people resulting in the rise in the average age of the individuals.

The report on Antibody Drug Conjugate Market by SMR comprises the following segmentation:

By Technology

• Non-cleavable Linker
• Cleavable Linker
• Linker less

By Application

• Breast Cancer
• Leukemia
• Lung Cancer
• Brain Tumor
• Lymphoma
• Myeloma
• Other Cancers

By Region

North America

• Canada
• USA
• Mexico
• The rest of North America

Europe

• Germany
• France
• United Kingdom
• Italy
• Spain
• Russia
• Rest of Europe

 Asia Pacific

• China
• India
• Japan
• South Korea
• Australia
• Rest of Asia Pacific

Latin America

• Argentina
• Brazil
• Rest of Latin America

Middle East and Africa

• South Africa
• Nigeria
• UAE
• Saudi Arabia
• Turkey

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 By Technology, “Cleavable Linker” has the highest and the most robust market share.

Cleavable linker technology offers superior adaptability, which means it offers more varied usages as compared to non–cleavable linkers. Cleavable linkers have the unique characteristic of using varied mechanisms to act on the disease site. In May 2022, Aptamer Group Plc and PinotBio announced that they would continue collaborating to develop four new drug conjugates using linker technology. This would ensure that the focused chemo-therapeutics would be developed for use soon.

By Application, “Breast Cancer” held the highest market share.

The number of breast cancer cases is on a spiralling rise. According to the WHO, the number of cases nearly doubled between 2000 and 2020, from 10 million cases to 19.3 million cases. Additionally, breast cancer has become the most prevalent form of cancer, surpassing lung cancer. Therefore, using ADCs as viable treatment options will also prevail, thereby increasing its market size.

 By Region, “North America” holds the highest market share.

North America will continue to hold the highest market share of ADCs as most of the development is done in the region, including the R&D and the clinical trials. The presence of many pharmaceutical companies based in the US, such as Johnson & Johnson, Pfizer, Gilead Sciences and Abbott International, will foster huge numbers in terms of revenue share.  The American Cancer Society has made a prediction of 1.9 million cancer cases and 609,000 deaths in 2022. With the rising cases of cancer in the region, it will enhance the market for ADCs.

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Key Players in the Antibody Drug Conjugate Market:

• Gilead Sciences Inc.
• Pfizer Inc.
• Daiichi Sankyo Company Ltd.
• GlaxoSmithKline Plc
• Seagen Inc.
• ADC Therapeutics
• ImmunoGen
• AstraZeneca Plc
• Genentech Inc.
• Mersana Therapeutics
• Amgen Inc.
• Sanofi

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Recent Developments in the Market:

• In June 2022, ADC Therapeutics was in the process of adding its second ADC to the portfolio of its company with its product –  camidanlumab tesirine. The drug showed promising results in phase 2 of the clinical trial. They are likely to apply for the FDA approval as an option to treat Hodgkin’s lymphoma.
• In June 2022, Spirea Limited announced that it had secured funding of GBP 2.4 million from investors to develop highly specialised ADCs in treating solid tumours. Their technology enables a higher ratio of drug to antibody, which means more amount of the drug is delivered to the affected area to remove the cancer cell. This would further help in the treatment of cancers.
• In May 2022, the FDA approved the use of fam-trastuzumab deruxtecan-nxki (Enhertu®), which was developed to treat metastatic HER2, which is a positive type of breast cancer. The drug was developed by Daiichi Sankyo and AstraZeneca.

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