Alzheimer’s-Infection Link; Women and Dementia; New Diagnostic Criteria for MOGAD

Do infections play a role in Alzheimer’s disease? (The Guardian)

The APOE R145C missense variant was linked with a higher risk of Alzheimer’s disease in people of African ancestry with the APOE3/4 genotype. (JAMA)

In the wake of news about Bruce Willis’s frontotemporal dementia diagnosis, Patti Davis, daughter of former President Ronald Reagan, recalls her father’s decision to make his Alzheimer’s disease diagnosis public. (New York Times)

Chronic alcohol exposure increased brain atrophy and altered behavior, metabolism, and Alzheimer’s-related pathology in mice. (Neurobiology of Disease)

Fighter pilots showed altered connectivity on functional MRI that may help identify brain changes in humans traveling to space. (Frontiers of Physiology)

In an analysis spanning six continents, women had higher dementia risk than men, particularly in countries with low- and lower-middle-income economies. (Alzheimer’s & Dementia)

Alpha-synuclein aggregates are excreted in stool and can be measured, which could support diagnoses of prodromal Parkinson’s disease and other synucleinopathies. (npj Parkinson’s Disease)

NIH researchers used computational modeling to uncover mutations in the human genome that may have been involved in critical developmental processes associated with cognition. (Science Advances)

The FDA approved deutetrabenazine extended-release tablets (Austedo XR), an additional formulation of the drug to treat tardive dyskinesia and chorea associated with Huntington’s disease, Teva Pharmaceuticals said.

An international panel proposed new criteria to diagnose myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). (Lancet Neurology)

Some Alzheimer’s research data by Stanford President and former Genentech executive Marc Tessier-Lavigne, PhD, may have been falsified, scientists alleged. (Stanford Daily)